Depression and anxiety in patients with hemophilia A and B

Author:

Koseoglu Fatos D1ORCID,Zuhal Demirci2,Onen-Sertoz Ozen3,Fahri Sahin2

Affiliation:

1. Department of Hematology, Faculty of Medicine, İzmir Bakırçay University, Izmir, Turkey

2. Department of Hematology, Adult Hemophilia Center, Faculty of Medicine, Ege University, Izmir, Turkey

3. Department of Psychiatry, Faculty of Medicine, Ege University, Izmir, Turkey

Abstract

Objective This study described the prevalence of and correlates of depression and anxiety in adult patients with hemophilia A and B. Methods In this cross-sectional study, we investigated patients with hemophilia who were being seen at an adult hemophilia center in Turkey. Participants were screened for depression and anxiety during their annual clinic visit, which included administration of the Beck Depression Inventory and State-Trait Anxiety Scale. Results Of the 90 patients, 22 (24.4%) met criteria for significant depressive symptoms and 67 (74.4%) met criteria for significant anxiety symptoms. There were no significant associations between depression and any psychosocial or clinical characteristics or adherence to hemophilia prophylaxis, except for educational status. No association was found between state and trait anxiety scores and psychosocial and clinical characteristics other than hemophilia type. After adjusting for confounding factors, multivariable analysis showed that high school education level was associated with depression (OR: 1.87, CI: 1.31–2.36, P = .010) and type B hemophilia was associated with anxiety (OR: 1.32, CI: 1.09–1.75, P = .042). Conclusion Depression and anxiety are major psychiatric comorbidities in patients with hemophilia in Turkey. Routine evaluation for mood and anxiety disorders are important in the routine care of patients with haemophilia.

Publisher

SAGE Publications

Subject

Psychiatry and Mental health

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