Depression and insomnia are independently associated with satisfaction and enjoyment of life in medication-overuse headache patients

Author:

Pompili Maurizio1,Innamorati Marco2,Lamis Dorian A3,Serafini Gianluca4,Ricci Federica1,Migliorati Monica1,Bellini Samantha1,Erbuto Denise1,Mazza Marianna5,Di Nicola Marco5,Janiri Luigi5,Gonda Xenia678,Rihmer Zoltan6,Amore Mario4,Girardi Paolo1,Martelletti Paolo9

Affiliation:

1. Department of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Center, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy

2. Department of Human Sciences, European University of Rome, Rome, Italy

3. Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia

4. Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, Section of Psychiatry, University of Genova, Genova, Italy

5. Institute of Psychiatry and Psychology, Catholic University of Sacred Heart, Rome, Italy

6. Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary

7. MTA-SE Neuropsychopharmacology Research Group, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary

8. Department of Pharmacodynamics, Semmelweis University, Hungary

9. Department of Clinical and Molecular Medicine, Sapienza University of Rome and Regional Referral Headache Centre, Sant'Andrea Hospital, Rome, Italy

Abstract

Objective Medication-overuse headache is often comorbid with emotional disturbances and disordered personality traits. The aim of the present study was to determine whether depression and insomnia complaints were associated with satisfaction and enjoyment with one’s own life in medication-overuse headache patients, and whether insomnia complaints were able to explain part of the variance of Quality of Life explained by depression. Methods Participants were 187 consecutive adult outpatients admitted to the Regional Referral Headache Centre of the Sant’Andrea Hospital in Rome, Italy. Patients were administered the Quality of Life Enjoyment and Satisfaction Questionnaire, the Beck Depression Inventory – II, and the Athens Insomnia Scale. Results The Beck Depression Inventory was associated with all the dimensions of the Quality of Life Enjoyment and Satisfaction Questionnaire, with more severe depression being associated independently with lower satisfaction and enjoyment with one’s own life. The Athens Insomnia Scale was independently and significantly associated only with physical health, such that patients with more insomnia complaints were 3.1 times ( p < 0.001) more likely to report lower physical health satisfaction. Conclusions Our findings confirmed that medication-overuse headache patients has a negative impact on quality of life and suggested that depression and insomnia were independently associated with satisfaction and enjoyment of life in medication-overuse headache patients. The early recognition and appropriate treatment of comorbid psychopathological symptoms are crucial to improve satisfaction and enjoyment of life in medication-overuse headache patients.

Publisher

SAGE Publications

Subject

Psychiatry and Mental health

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