Managing Acute Seizures: New Rescue Delivery Option and Resources to Assist School Nurses

Author:

Dean Patricia1,O’Hara Kathryn2,Brooks Lai3,Shinnar Ruth4,Bougher Genei5,Santilli Nancy6

Affiliation:

1. Epilepsy Program Specialist, Comprehensive Epilepsy Center, Nicklaus Children’s Hospital, Miami, FL

2. Clinical Research Nurse, Department of Neurology, Virginia Commonwealth University, Richmond, VA

3. Senior Director of the Neuroscience Institute, Le Bonheur Children’s Hospital, Memphis, TN

4. Consultant, New Rochelle, NY

5. Vice President/Subinvestigator, Northwest Florida Clinical Research Group, LLC, Gulf Breeze, FL

6. Global Managing Director, Human Care Systems, Boston, MA

Abstract

Approximately 470,000 children and adolescents in the United States have epilepsy, 30% of whom experience seizures despite antiseizure drug regimens. School nurses, teachers, caregivers, and parents play integral roles in implementing a care plan that avoids triggers, recognizes signs, and provides supportive care—ideally, guided by a patient-specific seizure action plan, which may include the use of rescue medication. Benzodiazepines are the mainstay of seizure rescue medication; for decades, rectally administered diazepam was the only approved rescue medication for seizure clusters outside the hospital setting. However, rectal administration has limitations that could delay treatment (e.g., social acceptability, removal of clothing, positioning). More recently, intranasal midazolam (for patients ≥12 years) and intranasal diazepam (for patients ≥6 years) were approved for this indication. Training and education regarding newer forms of rescue medication should improve confidence in the ability to treat seizures in school with the goal of increasing the safety of students with epilepsy.

Funder

Neurelis, Inc.

Publisher

SAGE Publications

Subject

General Medicine

Reference1 articles.

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