Making Meaningful Clinical Use of Biomarkers-Reference-Cited by-同舟云学术

Making Meaningful Clinical Use of Biomarkers

Published:2017-01-01 Issue: Volume:12 Page:117727191771523
ISSN:1177-2719
Container-title:Biomarker Insights
language:en
Short-container-title:Biomark�Insights

Author:

Selleck Matthew J¹,Senthil Maheswari¹,Wall Nathan R²

Affiliation:

1. Division of Surgical Oncology, Department of Surgery, Loma Linda University Medical Center, Loma Linda, CA, USA

2. Division of Biochemistry, Department of Basic Sciences and Center for Health Disparities & Molecular Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA

Abstract

This review discusses the current state of biomarker discovery for the purposes of diagnostics and therapeutic monitoring. We underscore relevant challenges that have defined the gap between biomarker discovery and meaningful clinical use. We highlight recent advancements in and propose a way to think about future biomarker development.

Publisher

SAGE Publications

Subject

Biochemistry (medical),Pharmacology,Molecular Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1177271917715236

Reference47 articles.

1. Predicting Clinical Outcomes Using Molecular Biomarkers

2. The Role of Proteomics in Biomarker Development for Improved Patient Diagnosis and Clinical Decision Making in Prostate Cancer

3. New Concepts in Cancer Biomarkers: Circulating miRNAs in Liquid Biopsies

4. Survivin is released from cancer cells via exosomes

5. The Role of Serum Alpha-Fetoprotein estimation in the Diagnosis and Management of Hepatocellular Carcinoma

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