Exosomes in Renal Cell Cancer: Diagnostic and Therapeutic Nanovehicles

Author:

Boussios Stergios12345ORCID,Ovsepian Saak V.67

Affiliation:

1. Department of Medical Oncology, Medway NHS Foundation Trust, Gillingham, UK

2. Faculty of Medicine, Health, and Social Care, Canterbury Christ Church University, Canterbury, UK

3. School of Cancer and Pharmaceutical Sciences, Faculty of Life Sciences and Medicine, King's College London, Strand, London, UK

4. Kent and Medway Medical School, University of Kent, Canterbury, UK

5. AELIA Organisation, Thessaloniki, Greece

6. Faculty of Engineering and Science, University of Greenwich London, Chatham Maritime, Kent, UK

7. Faculty of Medicine, Tbilisi State University, Tbilisi, Georgia

Abstract

Early diagnosis is crucial for enhancing the survival rate of renal cell cancer patients, and exosomes present potential advantages in this area. Their small size, high mobility, and lipid bilayer structure enable exosomes to cross biological membranes easily, protecting the bioactive cargo within from degradation. Exosomes significantly influence the invasion and metastasis of RCC, and they also contribute to tumor drug resistance and immune evasion.

Publisher

SAGE Publications

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