Multileaf Collimator Modeling and Commissioning for Complex Radiation Treatment Plans Using 2-Dimensional (2D) Diode Array MapCHECK2

Author:

Guo Jian1ORCID,Zhu Meng2,Zeng Weijin3,Wang He2,Qin Songbing1,Li Zhibin1,Tang Yu2,Ying Binbin4,Sang Jiugao5,Ji Ming2,Meng Kuo6,Hui Zhouguang6,Wang Jianyang6,Zhou Juying1,Zhou Yin7ORCID,Huan Jian8

Affiliation:

1. Department of Radiation Oncology, The First Affiliated Hospital of Soochow University, Suzhou, China

2. Qiusuo Health Technologies Inc., Suzhou, China

3. Department of Radiation Oncology, Yihui Foundation Hospital, Shanwei, China

4. Department of Stomatology, Ningbo First Hospital, Ningbo, China

5. Department of Radiation Oncology, Rudong County Hospital, Nantong, China

6. Department of Radiation Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

7. Homology Medical Technologies Inc., Ningbo, China

8. Department of Radiation Oncology, Suzhou Science and Technology Town Hospital, Suzhou, China

Abstract

Purpose: This study aims to develop a data-collecting package ExpressMLC and investigate the applicability of MapCHECK2 for multileaf collimator (MLC) modeling and commissioning for complex radiation treatment plans. Materials and methods: The MLC model incorporates realistic parameters to account for sophisticated MLC features. A set of 8 single-beam plans, denoted by ExpressMLC, is created for the determination of parameters. For the commissioning of the MLC model, 4 intensity modulated radiation therapy (IMRT) plans specified by the AAPM TG 119 report were transferred to a computed tomography study of MapCHECK2, recalculated, and compared to measurements on a Varian accelerator. Both per-beam and composite-beam dose verification were conducted. Results: Through sufficient characterization of the MLC model, under 3%/2 mm and 2%/2 mm criteria, MapCHECK2 can be used to accurately verify per beam dose with gamma passing rate better than 90.9% and 89.3%, respectively, while the Gafchromic EBT3 films can achieve gamma passing rate better than 89.3% and 85.7%, respectively. Under the same criteria, MapCHECK2 can achieve composite beam dose verification with a gamma passing rate better than 95.9% and 90.3%, while the Gafchromic EBT3 films can achieve a gamma passing rate better than 96.1% and 91.8%; the p-value from the Mann Whitney test between gamma passing rates of the per beam dose verification using full MapCHECK2 package calibrated MLC model and film calibrated MLC model is .44 and .47, respectively; the p-value between those of the true composite beam dose verification is .62 and .36, respectively. Conclusion: It is confirmed that the 2-dimensional (2D) diode array MapCHECK2 can be used for data collection for MLC modeling with the combination of the ExpressMLC package of plans, whose doses are sufficient for the determination of MLC parameters. It could be a fitting alternative to films to boost the efficiency of MLC modeling and commissioning without sacrificing accuracy.

Funder

Science and Technology Project of Nantong City

National Key Research and Development Program of China

National Natural Science Foundation of China

Jiangsu Provincial Medical Key Diiscipline

Publisher

SAGE Publications

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