Affiliation:
1. Department of Chemistry, University of Rajasthan, Jaipur, India
2. Department of Chemistry, Anurag Group of Institutions, Hyderabad, India
Abstract
A series of Zn(II) and Co(II) complexes have been synthesized by template condensation of bis(benzil)-4-chloro-1,2-phenylenediamine and bis(benzil)-4-fluoro-1,2-phenylenediamine, respectively, with 4-chloro-1,2-phenylenediamine and 4-fluoro-1,2-phenylenediamine in the presence of transition metal chlorides. The complexes have been characterized by physicochemical and spectroscopic techniques. Based on these studies, an octahedral geometry has been proposed around the metal ions. The newly synthesized ligands and their metal complexes have been screened for antimicrobial and anticancer activities. The in vitro cytotoxicity towards the HeLa cell line has been evaluated by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay.
Funder
university grants commission
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A review on designing and synthesis of lanthanide based macrocyclic complexes and their potential applications;Inorganica Chimica Acta;2024-02
2. Synthesis, Characterization, Biological Activity and Molecular Docking
Studies of Phthalic Acid based Macrocyclic Transition Metal Complexes;Asian Journal of Chemistry;2023
3. Synthesis, characterization, and antibacterial studies of some vanadium complexes with hexamethyl tetraazamacrocycles;Inorganic and Nano-Metal Chemistry;2022-03-10
4. One-pot synthesis and characterization of Schiff base macrocyclic complexes as a potential bioactive core – a review;Journal of Coordination Chemistry;2021-12-17
5. Spectroscopic, SOD, anticancer, antimicrobial, molecular docking and DNA binding properties of bioactive VO(IV), Cu(II), Zn(II), Co(II), Mn(II) and Ni(II) complexes obtained from 3-(2-hydroxy-3-methoxybenzylidene)pentane-2,4-dione;Journal of Biomolecular Structure and Dynamics;2020-08-14