Synthesis of Some Substituted Adamantane-2,4-diones from 4,4-Disubstituted Cyclohexanone Enamines and α,β-Unsaturated Acid Chlorides-Reference-Cited by-同舟云学术

Synthesis of Some Substituted Adamantane-2,4-diones from 4,4-Disubstituted Cyclohexanone Enamines and α,β-Unsaturated Acid Chlorides

Published:1999-05 Issue:5 Volume:23 Page:316-317
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Ahmed M. Giasuddin¹,Moeiz Syed M. Iqbal¹,Ahmed S. Asghari¹,Kiuchi Fumiyuki²,Tsuda Yoshisuke³,Sampson Paul⁴

Affiliation:

1. Department of Chemistry, University of Dhaka, Dhaka 1000, Bangladesh

2. Department of Pharmacognosy, Graduate School of Pharmaceutical science, Kyoto University, Yoshida, Sakyo-Ku, Kyoto 606-8501, Japan

3. Faculty of Pharmaceutical sciences, Kanazawa University, 13-1 Takara-Machi, Kanazawa 920, Japan

4. Department of Chemistry, Kent State University, USA

Abstract

Following our previous report7 on the synthesis of adamantane derivatives by condensation of 4,4-disubstituted cyclohexanone enamines with α,β-unsaturated acid chlorides, we now report the synthesis of seven new substituted adamantanediones from the reactions of three cyclohexanone enamines (4, Y = phenyl, isopropenyl, methyl) in which one of the substituents is an acetyl group.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.1177/174751989902300510

Reference7 articles.

1. Proton magnetic resonance spectra of substituted adamantane-2,4-diones. Determination of the C-6 and C-9 stereochemistry

2. BhaccaN. S. and WilliamsD. H., Application of NMR Spectroscopy in Organic Chemistry, Holden-Day, San Francisco, 1964, p. 184–190.

3. Proton magnetic resonance studies of cyclic compounds—iv

4. Substituent effects on the 13C chemical shifts of monosubstituted twistanes