Recurrent hepatobiliary sepsis in a patient with von Meyenburg complexes: a case report and review of the literature

Author:

Koay Doreen Siew Ching1,Leow Wei Qiang2,Tan Thuan Tong3,Slapak Gabrielle4

Affiliation:

1. Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore

2. Department of Pathology, Singapore General Hospital, Singapore

3. Department of Infectious Disease, Singapore General Hospital, Singapore

4. Department of Gastroenterology, Barking, Havering and Redbridge NHS Trust, UK

Abstract

The von Meyenburg complex (VMC) is a rare, congenital malformation of the ductal plate. It is typically asymptomatic and usually discovered incidentally. We report a unique case of recurrent life-threatening hepatobiliary sepsis caused by VMC and a review of the literature. A 62-year-old man presented with recurrent episodes of life-threatening hepatobiliary sepsis. Extensive investigations only showed that he has VMCs without any other source of sepsis or underlying immunodeficiency states. Despite prolonged courses of antibiotics which resolved each episode of sepsis, he suffers repeated recurrences of hepatobiliary sepsis. Liver transplantation is now being considered in view of his refractoriness to medical therapy. As VMC can present with severe hepatobiliary sepsis, it is therefore essential to recognise its presence. This case adds to the literature the atypical but life-threatening clinical presentation of VMC.

Publisher

SAGE Publications

Subject

General Medicine

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