Health-related quality of life among adolescents and young adults with mood and anxiety concerns

Author:

Kazi Ayman A12ORCID,Osuch Elizabeth A345,Wammes Michael345,John-Baptiste Ava14567ORCID

Affiliation:

1. Department of Epidemiology and Biostatistics, Western University, London, ON, Canada

2. Michael DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada

3. Department of Psychiatry, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada

4. London Health Sciences Centre, London, ON, Canada

5. Lawson Health Research Institute, London, ON, Canada

6. Schulich Interfaculty Program in Public Health, Western University, London, ON, Canada

7. Department of Anesthesia and Perioperative Medicine, Western University, London, ON, Canada

Abstract

Objectives To characterize health related quality of life (HRQOL) for Canadians aged 16 to 25 (adolescents and young adults, AYAs) seeking care for mood and anxiety concerns at the First Episode Mood and Anxiety Program, in London, Ontario and to identify factors associated with HRQOL in this population. Methods AYAs completed demographic, psychometric, and HRQOL questionnaires. We calculated 36-Item Short-Form Health Survey (SF-36) scores standardized to Canadian and US population norms. We computed Short Form 6 Dimension (SF-6D) utilities conducting multivariable linear regression analysis, adjusting for age, sex, ethnoracial minority status, parental marital/cohabitation status, parental education, the Anxiety Sensitivity Index (ASI-R), Montgomery-Åsberg Depression Rating Scale Self-Report (MADRS-S), Sheehan Disability Scale (SDS), and a modified Inventory of College Students’ Recent Life Experiences (ICSRLE-M). Results Amongst 182 AYAs who completed questionnaires, mean physical component summary (PCS), mental component summary (MCS) and SF-6D utility scores were low, 43.8 (SD = 16.6), 19.0 (SD = 11.9) and .576 (SD = .074), respectively. Maternal post-secondary education, depression (MADRS-S) and functional impairment (SDS) were significantly associated with SF-6D utility. Conclusion This cohort of mental healthcare-seeking AYAs had significantly impaired psychometric and utility-based measures of quality of life, underscoring the importance of timely access to healthcare services for this population.

Funder

London Health Sciences Centre

Schulich School of Medicine and Dentistry, University of Western Ontario

Lawson Health Research Institute

St. Joseph's Health Care

Canadian Depression Research and Intervention Network

London Health Sciences Foundation

Innovation Fund of the Alternate Funding Plan of the Academic Health Sciences Centres of Ontario

Publisher

SAGE Publications

Subject

Psychiatry and Mental health,Clinical Psychology,General Medicine,Pediatrics, Perinatology and Child Health

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