Case of Vibrio Vulnificus bacteremia in a patient heterozygous for HFE p.C282Y mutation and alcoholic liver cirrhosis

Author:

Strubchevska Kateryna1ORCID,Kozyk Marko1ORCID,Marijanovich Nicole1

Affiliation:

1. Corewell Health William Beaumont University Hospital, Royal Oak, MI, USA

Abstract

Vibrio vulnificus is a Gram-negative bacterium, a member of the Vibrionaceae family. V. vulnificus is the main cause of seafood-related deaths in the United States because it can cause severe wound infections or sepsis. This microorganism is highly dependent on iron availability. Therefore, patients with high body iron levels are more susceptible to the infection. Prompt treatment with cephalosporins as well as doxycycline is usually administered. We present a case of V. vulnificus bacteremia in a patient heterozygous for HFE p.C282Y mutation and underlying alcoholic liver cirrhosis.

Publisher

SAGE Publications

Subject

General Medicine

Reference14 articles.

1. Centers for Disease Control and Prevention. Vibrio species causing vibriosis, 2019, https://www.cdc.gov/vibrio/faq.html (accessed 2 December 2022).

2. Hemochromatosis, Iron, and Septicemia Caused by Vibrio vulnificus

3. Iron Overload in anHFEHeterozygous Carrier: A Case Report and Literature Review

4. Vibrio vulnificus Septicemia in a Patient With the Hemochromatosis HFE C282Y Mutation

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