A case of radiotherapy-induced bullous pemphigoid with unusually delayed onset: A case report-Reference-Cited by-同舟云学术

A case of radiotherapy-induced bullous pemphigoid with unusually delayed onset: A case report

Published:2023-01 Issue: Volume:11 Page:
ISSN:2050-313X
Container-title:SAGE Open Medical Case Reports
language:en
Short-container-title:SAGE Open Medical Case Reports

Author:

El Barch Maha¹^ORCID,Davar Sandra¹,Bélisle Annie²

Affiliation:

1. Division of Dermatology, Department of Medicine, Centre Hospitalier de l’Université de Montréal (CHUM), Montreal, Canada

2. Department of Pathology, Centre Hospitalier de l’Université de Montréal (CHUM), Montréal, Canada

Abstract

Bullous pemphigoid is an auto-immune blistering disease that generally affects older patients. Radiotherapy is one of the many triggering factors that have been described. Time to disease onset is variable; cases have been described during the course of radiotherapy while others have occurred up to 9 years later. We report a case of localized bullous pemphigoid on an irradiated site with unusual late presentation, 25 years after radiotherapy for left breast cancer. The pathophysiology of radiation-induced bullous pemphigoid is not clear, but the concept of an immunocompromised district seems to be a plausible explanation for the delayed onset of the disease.

Publisher

SAGE Publications

Subject

General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/2050313X231212991

Reference9 articles.

1. Bullous pemphigoid

2. Bullous pemphigoid and radiotherapy: case report and literature review update

3. The immunocompromised district: a unifying concept for lymphoedematous, herpes-infected and otherwise damaged sites

4. Bullous Pemphigoid: Trigger and Predisposing Factors

5. Bullous pemphigoid after radiation therapy