Some Sequential Tests in Clinical Trials Based on Randomized-Play-The-Winner Rule

Author:

Bandyopadhyay Uttam12,Biswas Atanu12

Affiliation:

1. Caicutta University

2. R. K. Mission Residential College, Narendrapur

Abstract

The present paper provides a nonpararnetric test procedure for comparing two treatments in clinical trials by using a sampling design which allocates more patients to the better treatment in course of decision making. Some exact and asymptotic results related to the performance characteristics and the properties of the proposed test are discussed and examined. Finally, the performance characteristics of the test are compared numerically with its possible competitors.

Publisher

SAGE Publications

Subject

General Medicine

Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Bayesian optimal response-adaptive design for binary responses using stopping rule;Statistical Methods in Medical Research;2016-05-02

2. Randomized Play-the-Winner Rule for Ordered Categorical Data;Communications in Statistics - Theory and Methods;2004-01

3. Generalized Delayed Response in Randomized Play-the-Winner Rule;Communications in Statistics - Simulation and Computation;2003-01-04

4. Adaptive designs for binary treatment responses in phase III clinical trials: controversies and progress;Statistical Methods in Medical Research;2001-10

5. A class of adaptive designs;Sequential Analysis;2000-01

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