Intrathecal drug delivery for the management of pain and spasticity in adults: British Pain Society’s recommendations for best clinical practice

Author:

Eldabe Sam1,Duarte Rui23ORCID,Thomson Simon4,Bojanic Stana5,Farquhar-Smith Paul6,Bagchi Somnath7,Farquhar Lis8ORCID,Wetherill Bill9,Copley Sue1ORCID

Affiliation:

1. Department of Pain Medicine, The James Cook University Hospital, Middlesbrough, UK

2. Liverpool Reviews and Implementation Group, Department of Health Data Science, University of Liverpool, Liverpool, UK

3. Saluda Medical Pty Ltd, Artarmon, NSW, Australia

4. Pain Medicine and Neuromodulation, Mid & South Essex University Hospitals, Essex, UK

5. Department of Neurosurgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

6. Department of Anaesthesia, Perioperative Medicine, Pain and Critical Care, The Royal Marsden NHS Foundation Trust, London, UK

7. Pain Medicine, University Hospitals Plymouth NHS Trust, Plymouth, UK

8. Pain Management Service, Leeds Teaching Hospitals NHS Trust, Leeds, UK

9. Main Pharmacy, The James Cook University Hospital, Middlesbrough, UK

Abstract

The British Pain Society updated their recommendations on intrathecal drug delivery (ITDD) for the management of pain and spasticity in adults. The recommendations are primarily evidence based but where necessary comprise the consensus opinion of the working group. The recommendations are accompanied by information for patients and their carers, intended to inform and support patients in their decision making. The updated guidance includes recent evidence base of ITDD use in pain and spasticity, address the issues of drug pump compatibility following the latest manufacturer and Medicines and Healthcare products Regulatory Agency (MHRA) recommendations as well as provide an update on the indications and complication management particularly endocrine complications and intrathecal granuloma formation.

Publisher

SAGE Publications

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