The Australian, US, Scandinavian Imaging Exchange (AUSSIE): an innovative, virtually-integrated health research network embedded in health care

Author:

Looi Jeffrey CL1,Velakoulis Dennis2,Walterfang Mark2,Georgiou-Karistianis Nellie3,Macfarlane Matthew D1,Power Brian D4,Nilsson Christer5,Styner Martin6,Thompson Paul M7,Van Westen Danielle8,Wilkes Fiona A9,Wahlund Lars-Olof10

Affiliation:

1. Academic Unit of Psychiatry and Addiction Medicine, Australian National University Medical School, Canberra, and; Mental Health Service, Australian Capital Territory Health Directorate, Canberra Hospital, Woden, ACT, Australia

2. Neuropsychiatry Unit, Royal Melbourne Hospital, Melbourne, and; Melbourne Neuropsychiatry Centre, University of Melbourne and Northwestern Mental Health, Melbourne, VIC, Australia

3. School of Psychology and Psychiatry, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, Australia

4. School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley; and; Peel and Rockingham Kwinana Mental Health Service, Rockingham, WA, Australia

5. Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Lund, Sweden

6. Departments of Psychiatry and Computer Science, University of North Carolina, Chapel Hill, NC, USA

7. Imaging Genetics Center, University of Southern California (USC) Institute for Neuroimaging and Informatics, Keck School of Medicine, USC, Marina del Rey, CA, USA; Departments of Neurology and Psychiatry, University of California at Los Angeles (UCLA) School of Medicine, UCLA, CA, USA; and Departments of Neurology, Psychiatry, Engineering, Radiology and Ophthalmology, Keck School of Medicine, USC, USA

8. Center for Medical Imaging and Physiology, Skåne University Hospital, Lund, and; Diagnostic Radiology, Department of Clinical Sciences, Lund University, Lund, Sweden

9. Academic Unit of Psychiatry and Addiction Medicine, ANU Medical School, Canberra, and; Mental Health Service, ACT Health Directorate, Canberra Hospital, Woden, ACT, Australia

10. Department of Neurobiology, Care Sciences and Society, Division of Clinical Geriatrics, Karolinska Institute, Stockholm, Sweden

Abstract

Objective: To describe the development, design and function of an innovative international clinical research network for neuroimaging research, based in Australia, within a joint state health service/medical school. This Australian, US, Scandinavian Imaging Exchange (AUSSIE) network focuses upon identifying neuroimaging biomarkers for neuropsychiatric and neurodegenerative disease. Methods: We describe a case study of the iterative development of the network, identifying characteristic features and methods which may serve as potential models for virtual clinical research networks. This network was established to analyse clinically-derived neuroimaging data relevant to neuropsychiatric and neurodegenerative disease, specifically in relation to subcortical brain structures. Results: The AUSSIE network has harnessed synergies from the individual expertise of the component groups, primarily clinical neuroscience researchers, to analyse a variety of clinical data. Conclusion: AUSSIE is an active virtual clinical research network, analogous to a connectome, which is embedded in health care and has produced significant research, advancing our understanding of neuropsychiatric and neurodegenerative disease through the lens of neuroimaging.

Publisher

SAGE Publications

Subject

Psychiatry and Mental health

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