Effects of bone morphogenetic proteins on epithelial repair

Author:

Hou Yu12,He Yu-Xi1,Zhang Jia-Hao12,Wang Shu-Rong1,Zhang Yan1ORCID

Affiliation:

1. Department of Ophthalmology, 2nd Hospital of Jilin University, Changchun 130041, China

2. Norman Bethune Health Science Center of Jilin University, Changchun 130021, China

Abstract

Epithelial tissue has important functions such as protection, secretion, and sensation. Epithelial damage is involved in various pathological processes. Bone morphogenetic proteins (BMPs) are a class of growth factors with multiple functions. They play important roles in epithelial cells, including in differentiation, proliferation, and migration during the repair of the epithelium. This article reviews the functions and mechanisms of the most profoundly studied BMPs in the process of epithelial damage repair and their clinical significance.

Funder

Jilin Provincial Science and Technology Department International Science and Technology Cooperation Project

Course Cases Base of Professional Degree Graduate

the Outstanding Young Teacher Training Program of Jilin University

Jilin Province traditional Chinese medicine science and technology support project

The Mechanism of BMP4 Inhibiting Corneal Neovascularization

Jilin Medical and Health Talents Special Project

Youth Talent Training Project of Jilin Provincial Department of Finance

Natural Science Foundation of Science and Technology Department of Jilin Province

Publisher

SAGE Publications

Subject

General Biochemistry, Genetics and Molecular Biology

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