High Rate Multiple Drug Resistances in HIV-Infected Patients Failing Nonnucleoside Reverse Transcriptase Inhibitor Regimens in Thailand, Where Subtype A/E is Predominant-Reference-Cited by-同舟云学术

High Rate Multiple Drug Resistances in HIV-Infected Patients Failing Nonnucleoside Reverse Transcriptase Inhibitor Regimens in Thailand, Where Subtype A/E is Predominant

Published:2006-12 Issue:4 Volume:5 Page:152-156
ISSN:1545-1097
Container-title:Journal of the International Association of Physicians in AIDS Care
language:en
Short-container-title:Journal of the International Association of Physicians in AIDS Care

Author:

Chetchotisakd Ploenchan¹,Anunnatsiri Siriluck²,Kiertiburanakul Sasisopin³,Sutthent Ruengpung,Anekthananon Thanomsak⁴,Bowonwatanuwong Chureeratana⁵,Kowadisaiburana Boonchai⁶,Supparatpinyo Khuanchai⁷,Horsakulthai Manassinee²,Chasombat Sanchai⁸,Ruxrungtham Kiat⁹,Team the Study

Affiliation:

1. Srinagarind Hospital, Khon Kaen University, Khon Kaen 40002, Thailand;

2. Srinagarind Hospital, Khon Kaen University, Khon Kaen

3. Ramathibodi Hospital, Mahidol University, Bangkok

4. Siriraj Hospital, Mahidol University, Bangkok

5. Chonburi Hospital, Chonburi

6. Bamrasnaradura Institute, Nonthaburi

7. Chiang Mai University Hospital, Chiang Mai University, Chiang Mai

8. Bureau of AIDS, TB, and STI, Department of Disease Control, Ministry of Public Health, Thailand

9. Chulalongkorn University Hospital, Chulalongkorn University; HIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok

Abstract

The prevalence of drug resistance was determined among 64 HIV-infected Thai patients who were failed while receiving nonnucleoside reverse transcriptase inhibitor (NNRTI)–based regimens. Eighty-nine percent of patients had 1 or more NNRTI mutation resistances. Almost all patients had resistance to at least 1 nucleoside reverse transcriptase inhibitor (NRTI), and 42% had multiple-NRTI resistance.

Publisher

SAGE Publications

Subject

Infectious Diseases,Dermatology,Immunology

Link

http://journals.sagepub.com/doi/pdf/10.1177/1545109706294288

Reference16 articles.

1. Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection

2. British HIV Association (BHIVA) guidelines for the treatment of HIV-infected adults with antiretroviral therapy (2005)

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. High prevalence of PI resistance in patients failing second-line ART in Vietnam;Journal of Antimicrobial Chemotherapy;2015-12-11

2. Virological Failure and HIV-1 Drug Resistance Mutations among Naive and Antiretroviral Pre-Treated Patients Entering the ESTHER Program of Calmette Hospital in Cambodia;PLoS ONE;2014-08-28

3. Decreased Phenotypic Susceptibility to Etravirine in Patients with Predicted Genotypic Sensitivity;PLoS ONE;2014-07-07

4. Do HIV-1 non-B subtypes differentially impact resistance mutations and clinical disease progression in treated populations? Evidence from a systematic review;Journal of the International AIDS Society;2014-01

5. Extensive Drug Resistance in HIV-Infected Cambodian Children Who Are Undetected as Failing First-Line Antiretroviral Therapy by WHO 2010 Guidelines;AIDS Research and Human Retroviruses;2013-07