Cleft lip and palate

Author:

Lotfallah Andrew12ORCID,Shahidi Shayan3ORCID,Odelberg Sven Wilhelm4,Darr Adnan5

Affiliation:

1. ENT Registrar, University Hospitals Birmingham NHS Foundation Trust, Birmingham

2. Email:

3. ENT Registrar, Department of Otolaryngology, Queen Alexandra Hospital, Portsmouth

4. Anatomy demonstrator, Cambridge University Hospitals NHS Foundation Trust, Cambridge

5. Consultant ENT Surgeon, University Hospitals Coventry and Warwickshire NHS Trust, Coventry

Abstract

The term ‘oral cleft’ describes a spectrum of oro-facial developmental malformations in which there is an abnormal anatomical opening or division of the lip, palate or both. There are three main types: cleft lip (CL) alone, cleft lip with cleft palate (CL/CP), and cleft palate (CP) alone. They represent the most common facial anomaly worldwide. This article describes the embryological theory, aetiology, diagnosis and management of oral clefting, focusing on the functional impact of the condition, how patients may present, and clinical findings which may raise suspicion in primary care.

Publisher

SAGE Publications

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference32 articles.

1. BAPRAS (2015) Cleft lip and palate. Available at: www.bapras.org.uk/public/patient-information/surgery-guides/cleft-lip-and-palate (accessed 10 January 2022).

2. Genetic factors influencing risk to orofacial clefts: today’s challenges and tomorrow’s opportunities

3. CLAPA (2015) CLAPA Conference 2015 videos. Available at: www.clapa.com/news-item/clapa-conference-2015-videos/ (accessed 15 November 2021).

4. Nitrofurantoin and congenital abnormalities

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