Affiliation:
1. National Institutes of Health, Bethesda 14, Maryland
Abstract
A histochemical method for the demonstration of a γ-glutamyl transpeptidase-like enzymic activity using N(γ-glutamyl)β-naphthylamide as substrate in a simultaneous diazonium coupling reaction has revealed many tissue localizations distinct from those noted with other peptidase substrates. The biochemical and histochemical evidence presented suggests that at the pH of the histochemical reaction both a transpeptidase and hydrolytic reaction mediated by the same enzyme occurs and, as indicated by histochemical inhibitor studies, the characteristics of the activity appear to be identical with those of γ-glutamyl transpeptidase as defined biochemically.
Cited by
189 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献