Novel 3D printed TPMS scaffolds: microstructure, characteristics and applications in bone regeneration

Author:

Ma Jiaqi1ORCID,Li Yumeng1,Mi Yujing2,Gong Qiannan3,Zhang Pengfei4,Meng Bing1,Wang Jue5,Wang Jing6,Fan Yawei1

Affiliation:

1. Department of Oral and Maxillofacial Surgery, First Hospital of Shanxi Medical University, Taiyuan, China

2. Department of Orthodontics, First Hospital of Shanxi Medical University, Taiyuan, China

3. Shanxi Provincial People’s Hospital of Stomatology,Taiyuan,China

4. Shanxi Medical University School and Hospital of Stomatology, Taiyuan, China

5. Department of Prosthodontics, First Hospital of Shanxi Medical University, Taiyuan, China

6. State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Oral Implants, School of Stomatology, The Fourth Military Medical University, Xi’an, People’s Republic of China

Abstract

Bone defect disease seriously endangers human health and affects beauty and function. In the past five years, the three dimension (3D) printed radially graded triply periodic minimal surface (TPMS) porous scaffold has become a new solution for repairing bone defects. This review discusses 3D printing technologies and applications for TPMS scaffolds. To this end, the microstructural effects of 3D printed TPMS scaffolds on bone regeneration were reviewed and the structural characteristics of TPMS, which can promote bone regeneration, were introduced. Finally, the challenges and prospects of using TPMS scaffolds to treat bone defects were presented. This review is expected to stimulate the interest of bone tissue engineers in radially graded TPMS scaffolds and provide a reliable solution for the clinical treatment of personalised bone defects.

Publisher

SAGE Publications

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