HTLV-1 uveitis in Colombia, an underrecognized complication of a hitherto neglected condition: a case series

Author:

Villamil-Gomez Wilmer1ORCID,Torres Jaime R.2,Rojas-Hernández Juan3,Merlano Jose Ignacio Restom4,Vergara-Corena Jairo5,Salgado Patricia6,Viloria-Ruiz Jorge7,Castro Alvaro8,Cabrera Lasso Andrés Mauricio6,Gotuzzo Eduardo9

Affiliation:

1. Centro de Investigación en Ciencias de la Vida, Grupo de expertos Clinicos , Secretaria de salud de Barranquilla, Universidad Simón Bolívar, Barranquilla, Colombia

2. Infectious Diseases Section, Tropical Medicine Institute, Universidad Central de Venezuela, Caracas, Venezuela

3. GRINPED Research Group, Universidad Libre Seccional Cali, Cali, Colombia

4. Dirección Científica, Clinica Oftalmologica de la Costa, Sincelejo, Colombia

5. Departamento de Medicina Interna, Universidad de Sucre, Sincelejo, Colombia

6. Infectious Diseases and Infection Control Research Group, Hospital Universitario de Sincelejo, Sincelejo, Colombia

7. Facultad de Medicina, Universidad de Sucre, Sincelejo, Colombia

8. Departamento de Patología, Universidad de Sucre, Sincelejo, Colombia

9. Universidad Peruana Cayetano Heredia, Lima, Peru

Abstract

Three Colombian patients with chronic HTLV-1 infection and severe intermediate and/or posterior uveitis are described. In one case, retinal ablation was necessary due to extensive peripheral degeneration, while the other two were successfully managed with local anti-inflammatory therapy. Gradual resolution of ocular findings was observed in all three patients on follow-up. Uveitis is a rarely recognized late complication of this infection, which represents a diagnostic and therapeutic challenge for clinicians in endemic countries. The real extension of HTLV-1 prevalence in Colombia and the frequency of its ophthalmologic complications remain to be determined.

Publisher

SAGE Publications

Subject

Pharmacology (medical),Infectious Diseases

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