Comparing Lookback Periods to Ascertain Alzheimer’s Disease and Related Dementias

Author:

Kunicki Zachary J.12ORCID,Bayer Thomas23ORCID,Jiang Lan2,Bozzay Melanie L.4,Quinn McKenzie J.5,De Vito Alyssa N.1ORCID,Emrani Sheina1,Erqou Sebhat15,McGeary John E.12,Zullo Andrew R.26,Duprey Matthew S.7,Singh Mriganka236,Primack Jennifer M.12,Kelso Catherine M.58,Wu Wen-Chih23ORCID,Rudolph James L.23

Affiliation:

1. Department of Psychiatry & Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA

2. VA Center of Innovation in Long Term Services, Providence VA Medical Center, Providence, RI, USA

3. Department of Medicine, Alpert Medical School of Brown University, Providence, RI, USA

4. Wexner Medical Center, The Ohio State University, Columbus, OH, USA

5. VA RR&D Center for Neurorestoration and Neurotechnology, Providence VA Medical Center, Providence, RI, USA

6. Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI, USA

7. Department of Pharmacy, University of Kentucky, Lexington, KY, USA

8. Office of Patient Care Services, Geriatrics and Extended Care, Veterans Health Administration, Washington, DC, USA

Abstract

Claims data are a valuable resource for studying Alzheimer’s disease and related dementias (ADRD). Alzheimer’s disease and related dementias is often identified using a list of claims codes and a fixed lookback period of 3 years of data. However, a 1-year lookback or an approach using all-available lookback data could be beneficial based on different research questions. Thus, the purpose of this study was to compare 1-year and all-available lookback approaches to ascertaining ADRD compared to the standard 3-year approach. Using a cohort of Veterans hospitalized for heart failure (N = 373, 897), our results suggested high agreement (93% or greater) between the lookback periods. The 1-year lookback period had lower sensitivity (60%) and underestimated the prevalence of ADRD. These results suggest that 1-year and all-available lookback periods are viable approaches when using claims data.

Publisher

SAGE Publications

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Neuroscience

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