The Impact of Exercise, Cognitive Activities, and Socialization on Cognitive Function

Author:

Jedrziewski M. Kathryn1234,Ewbank Douglas C.5,Wang Haidong6,Trojanowski John Q.12347

Affiliation:

1. The Institute on Aging, University of Pennsylvania, Philadelphia, PA, USA

2. Marian S. Ware Alzheimer Program, University of Pennsylvania, Philadelphia, PA, USA

3. Alzheimer’s Disease Core Center, University of Pennsylvania, Philadelphia, PA, USA

4. Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

5. Population Studies Center, University of Pennsylvania, Philadelphia, PA, USA

6. Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA

7. Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia, PA, USA

Abstract

Currently, there are no effective treatments for Alzheimer’s disease and related disorders and age continues to be a robust risk factor. Thus, population aging in the United States may have catastrophic results if interventions are not found and implemented. This study examines possible associations between cognitive impairment and exercise, cognitive activities, and socialization. Cognitive activities, socialization, and exercise were assessed at baseline, and cognitive function was measured at baseline, 5-year, and 10-year follow-up. Controlling for baseline cognitive function, age, sex, education, diabetes, and hypertension, linear regression was performed. Engagement in cognitive activities was inversely associated with the onset of cognitive impairment at 5-year follow-up but was no longer significant at 10-year follow-up. Exercise was associated with a lower risk of cognitive impairment at 10-year follow-up but was not significant at 5-year follow-up. Associations with socialization were not statistically significant at either follow-up.

Publisher

SAGE Publications

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Neuroscience

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