Early Versus Delayed Microdiscectomy for Chronic Sciatica Lasting 4–12 Months Secondary to Lumbar Disc Herniation: A Secondary Analysis of a Randomized Controlled Trial

Author:

Bailey Christopher S.123,Glennie Andrew12,Rasoulinejad Parham123,Kanawati Andrew12ORCID,Taylor David1,Sequeira Keith4ORCID,Miller Thomas235,Watson Jim6ORCID,Rosedale Richard7,Bailey Stewart I.123,Gurr Kevin R.123,Siddiqi Fawaz123,Urquhart Jennifer C.13ORCID

Affiliation:

1. Department of Surgery, London Health Sciences Center, London, Ontario, Canada

2. Schulich School of Medicine and Dentistry, Western University, London, Ontario Canada

3. Lawson Health Research Institute, London, Ontario, Canada

4. Regional Rehab and Spinal Cord Injury Outpatients, Parkwood Institute, London, Ontario, Canada

5. Department of Physical Medicine and Rehabilitation, St. Joseph’s Health Care London, London, Ontario, Canada

6. Department of Anesthesia and Perioperative Medicine, St. Joseph’s Health Care London, London, Ontario, Canada

7. Occupational Health and Safety, London Health Sciences Centre, London, Ontario, Canada

Abstract

Objectives To compare the effect of delaying surgery on clinical outcome in patients with chronic sciatica secondary to lumbar disc herniation. Methods Patients with sciatica lasting 4–12 months and lumbar disc herniation at the L4–L5 or L5–S1 level were randomized to undergo microdiscectomy (early surgery) or to receive 6 months of nonoperative treatment followed by surgery if needed (delayed surgery). Outcomes were leg pain, Oswestry Disability Index score (ODI), back pain, SF–36 physical component (PCS) and mental component (MCS) summary scores, employment, and satisfaction measured preoperatively and at 6 weeks, 3 months, 6 months, and 1 year after surgery. Results Of the 64 patients in the early surgery group, 56 underwent microdiscectomy an average of 3 ± 2 weeks after enrollment. Of the 64 patients randomized to nonoperative care, 22 patients underwent delayed surgery an average of 53 ± 24 weeks after enrollment. The early surgery group experienced less leg pain than the delayed surgery group, which was the primary outcome, at 6 months after surgery (early surgery 2.8 ± .4 vs delayed surgery 4.8 ± .7; difference, 2.0; 95% confidence interval, .5–3.5). The overall estimated mean difference between groups significantly favored early surgery for leg pain, ODI, SF36-PCS, and back pain. The adverse event rate was similar between groups. Conclusions Patients presenting with chronic sciatica treated with delayed surgery after prolonging standardized non-operative care have inferior outcomes compared to those that undergo expedited surgery.

Publisher

SAGE Publications

Subject

Clinical Neurology,Orthopedics and Sports Medicine,Surgery

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1. 1. Lumbosacral radicular pain;Pain Practice;2023-11-20

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