What Is the Evidence Supporting Osteobiologic Use in Revision Anterior Cervical Discectomy and Fusion?

Author:

Muthu Sathish12ORCID,Diniz Sara Elisa3,Viswanathan Vibhu Krishnan24,Hsieh Patrick C.5,Abedi Aidin67,Yoon Tim8ORCID,Meisel Hans Jörg9ORCID,Buser Zorica1011ORCID,Rodrigues-Pinto Ricardo31213ORCID,Knowledge Forum Degenerative AO Spine14

Affiliation:

1. Department of Orthopaedics, Government Medical College, Dindigul, India.

2. Orthopaedic Research Group, Coimbatore, Tamil Nadu, India.

3. Department of Orthopaedics, Centro Hospitalar Universitário do Porto, Porto, Portugal

4. Department of Musculoskeletal Oncology, University of Calgary, Alberta, CA

5. Department of Neurological Surgery, USC Spine Center, Keck School of Medicine, Los Angeles, CA, USA

6. Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

7. USC Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

8. Department of Orthopaedics, Emory University, Atlanta, GA, USA

9. Department of Neurosurgery, BG Klinikum Bergmannstrost Halle, Germany

10. Gerling Institute, Brooklyn, NY, USA

11. Department of Orthopedic Surgery, NYU Grossman School of Medicine, New York, USA

12. Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Portugal

13. Hospital CUF Trindade, Porto, Portugal

14. AO Spine, AO Foundation, Davos, Switzerland

Abstract

Study design Systematic literature review Objective To analyze the literature and describe the evidence supporting osteobiologic use in revision anterior cervical discectomy and fusion (ACDF) surgery. Methods A systematic search of PubMed/MEDLINE, EMBASE, Cochrane library, and ClinicalTrials.gov databases was conducted for literature reporting the use of osteobiologics in revision ACDF. We searched for studies reporting outcomes of using any osteobiologic use in revision ACDF surgeries (independently of the number of levels) in the above databases. Results There are currently no studies in the literature describing the outcome and comparative efficacy of diverse osteobiologic agents in the context of revision ACDF surgery. A majority of the current evidence is based only upon studies involving primary ACDF surgery. Conclusion The current study highlights the paucity of literature evidence on the role of diverse osteobiologics in revision ACDF, and foregrounds the need for high-quality evidence on this subject.

Publisher

SAGE Publications

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3