The Management of Symptomatic Lumbar Disc Herniation in Pregnancy: A Systematic Review

Author:

Whiles Emily1ORCID,Shafafy Roozbeh2ORCID,Valsamis Epaminondas Markos3,Horton Chris4,Morassi Giuseppe Lambros1,Stokes Oliver5,Elsayed Sherief16

Affiliation:

1. Brighton & Sussex University Hospitals NHS Trust, Brighton, UK

2. Royal London Hospital, Barts Health NHS Trust, London, UK

3. Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Trust, Oxford, UK

4. Sir William Dunn School of Pathology, University of Oxford, Oxford, UK

5. Royal Devon & Exeter NHS Foundation Trust, London, UK

6. NMC Spine, Dubai, United Arab Emirates

Abstract

Study Design: Systematic review. Objectives: Lumbar disc herniation (LDH) has been reported to affect 1 in 10 000 pregnant women. There is limited evidence available regarding the optimal management of LDH in pregnant patients. We aimed to review the current evidence for the management of symptomatic LDH in pregnancy through critical appraisal and analysis of the available literature. Methods: Searches were conducted in Medline, Embase, PubMed, Science Direct, and The Cochrane Library from inception using predetermined search terms. All peer-reviewed studies of pregnant women with symptomatic LDH were included. The quality of eligible articles was assessed and extracted data and characteristics were pooled for analysis. References cited by studies were screened to identify other relevant publications. Results: Thirty studies involving 52 patients were identified. Compared to surgically managed patients, conservatively managed patients had a higher full recovery rate (61.54% vs 56.41%) and reported a lower rate of persistent symptoms (30.77% vs 38.54%). Compared to patients who were treated surgically for cauda equina syndrome, patients treated surgically for sciatica had a higher full recovery rate (80.95% vs 27.78%) and reported a lower rate of persistent symptoms (14.29% vs 66.67%). Conclusion: There is limited evidence to guide the management of pregnant patients with LDH. Despite a suggestion toward improved outcomes with conservative management, the presence of selection bias and the overall poor quality of current research precludes reliable conclusions from being drawn. Decision making for this patient group should be undertaken within a multidisciplinary setting.

Publisher

SAGE Publications

Subject

Neurology (clinical),Orthopedics and Sports Medicine,Surgery

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