Predicting Mechanical Failure Following Cervical Deformity Surgery: A Composite Score Integrating Age-Adjusted Cervical Alignment Targets

Author:

Lafage Renaud1ORCID,Smith Justin S2ORCID,Soroceanu Alexandra3,Ames Christopher4,Passias Peter5,Shaffrey Christopher6,Mundis Gregory7,Alshabab Basel Sheikh8,Protopsaltis Themistocles5,Klineberg Eric9,Elysee Jonathan1,Kim Han Jo1ORCID,Bess Shay10,Schwab Frank8,Lafage Virginie8ORCID,

Affiliation:

1. Department of Orthopedics, Hospital for Special Surgery, New York, NY, USA

2. Department of Neurosurgery, University of Virginia Medical Center, Charlottesville, VA, USA

3. Department of Surgery, University of Calgary, Calgary, AB, Canada

4. Department of Neurological Surgery, University of California, San Francisco, School of Medicine, San Francisco, CA, USA

5. Department of Orthopedics, NYU Langone Orthopedic Hospital, New York, NY, USA

6. Department of Neurosurgery, Duke University Medical Center, Durham, NC, USA

7. Scripps Clinic, San Diego, CA, USA

8. Department of Orthopaedic Surgery, Northwell Health, Lenox Hill Hospital, New York, NY, USA

9. Department of Orthopaedic Surgery, University of California, Davis, CA, USA

10. Denver International Spine Center, Presbyterian St. Luke’s/Rocky Mountain Hospital for Children, Denver, CO, USA

Abstract

Study Design Retrospective cohort study. Objectives Investigate a composite score to evaluate the relationship between alignment proportionality and risk of distal junctional kyphosis (DJK). Methods 84 patients with minimum 1 year follow-up were included (age = 61.1 ± 10.3 years, 64.3% women). The Cervical Score was constructed using offsets from age-adjusted normative values for sagittal vertical axis (SVA), T1 Slope (TS), and TS minus cervical lordosis (CL). Individual points were assigned based on offset with age-adjusted alignment targets and summed to generate the Cervical Score. Rates of mechanical failure (DJK revision or severe DJK [DJK> 20° and ΔDJK> 10°]) were assessed overall and based on Cervical Score. Logistical regressions assessed associations between early radiographic alignment and 1-year failure rate. Results Mechanical failure rate was 21.4% (N = 18), 10.7% requiring revision. By multivariate logistical regression: 3-month T1S (OR: .935), TS-CL (OR:0.882), and SVA (OR:1.015) were independent predictors of 1-year failure (all P < .05). Cervical Score ranged (−6 to 6), 37.8% of patients between −1 and 1, and 50.0% with 2 or higher. DJK patients had significantly higher Cervical Score (4.1 ± 1.3 vs .6 ± 2.2, P < .001). Patients with a score ≥3 were significantly more likely to develop a failure (71.4%) with OR of 38.55 (95%CI [7.73; 192.26]) and Nagelkerke r2 .524 (P < .001) Conclusion This study developed a composite alignment score predictive of mechanical failures in CD surgery. A score ≥3 at 3 months following surgery was associated with a marked increase in failure rate. The Cervical Score can be used to analyze sagittal alignment and help define realignment objectives to reduce mechanical failure.

Publisher

SAGE Publications

Subject

Neurology (clinical),Orthopedics and Sports Medicine,Surgery

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