The Influence of Multilevel Spinal Deformity Surgery on the EuroQol 5 Dimensions’ (EQ-5D) Questionnaire and Residential Status in the Elderly: A Prospective, Observational, Multicenter Study

Author:

Jentzsch Thorsten123ORCID,Lewis Stephen J.1ORCID,Oitment Colby4ORCID,Rienmüller Anna5,Martin Allan R.6,Nielsen Christopher J.1,Shear-Yashuv Hananel7,de Kleuver Marinus8,Qiu Yong9ORCID,Matsuyama Yukihiro10,Lenke Lawrence G.11,Alanay Ahmet12,Pellisé-Urquiza Ferran13,Cheung Kenneth M. C.14ORCID,Spruit Maarten15,Polly David W.16,Sembrano Jonathan N.16,Shaffrey Christopher I.17,Smith Justin S.18,Kelly Michael P.19ORCID,Dahl Benny2021,Berven Sigurd H.22,

Affiliation:

1. Division of Orthopaedic Surgery, Arthritis Program, Toronto Western Hospital, University Health Network, Toronto, ON, Canada

2. Department of Surgery, University of Toronto, Toronto, ON, Canada

3. Department of Orthopaedics, University of Zurich, Balgrist University Hospital, Zurich, Switzerland

4. Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada, Canada

5. Department of Orthopedic and Trauma Surgery, Medical University Vienna, Vienna, Austria

6. Department of Neurological Surgery, University of California - Davis, Sacramento, CA, USA

7. Department of Orthopaedic, Hebrew University, Hadassah Medical Center, Jerusalem, Israel

8. Department of Orthopedics, Medical Center, Radboud University, Nijmegen, Gelderland, The Netherlands

9. Spine Surgery, Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China

10. Department of Orthopedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan

11. Department of Orthopedic Surgery, The Spine Hospital, Medical Center, Columbia University, New York, NY, USA

12. Department of Orthopedics and Traumatology, Acibadem Mehmet ali Aydinlar University, Istanbul, Turkey

13. Hospital Universitari de la Vall d’Hebron, Barcelona, Spain

14. Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong

15. Sint Maartenskliniek Nijmegen, Gelderland, the Netherlands

16. Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN, USA

17. Department of Orthopaedic Surgery, Duke University, Durham, NC, USA

18. Department of Neurosurgery, University of Virginia, Charlottesville, VA, USA

19. Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO, USA

20. Division of Orthopedic Surgery, Texas Children's Hospital and Baylor College of Medicine, Houston, TX, USA

21. Spine Unit, Rigshospitalet, University of Copenhagen, Denmark

22. Department of Neurosurgery and Orthopaedic Surgery, University of California, San Francisco, CA, USA

Abstract

Study Design Multicenter, international prospective study. Objective This study investigated the clinical outcome up to 2 years after multi-level spinal deformity surgery in the elderly by reporting the minimal clinically important difference (MCID) of EuroQol 5-dimensions (EQ-5D), EQ-VAS, and residential status. Methods As an ancillary study of 219 patients ≥60 years with spinal deformity undergoing primary instrumented fusion surgery of ≥5 levels, this study focuses on EQ-5D (3-L) as the primary outcome and EQ-VAS and residential status as secondary outcomes. Data on EQ-5D were compared between pre-operatively and postoperatively at 10 weeks, 12 months, and 24 months. An anchor-based approach was used to calculate the MCID. Results The EQ-5D index and EQ-VAS, respectively, improved significantly at each time point compared to pre-operatively (from .53 (SD .21) and 55.6 (SD 23.0) pre-operatively to .64 (SD .18) and 65.8 (SD 18.7) at 10 weeks, .74 (SD .18) and 72.7 (SD 18.1) at 12 months, and .73 (SD .20) and 70.4 (SD 20.4) at 24 months). 217 (99.1%) patients lived at home pre-operatively, while 186 (88.6%), 184 (98.4%), and 172 (100%) did so at 10 weeks, 12 months, and 24 months, respectively. Our calculated MCID for the EQ-5D index at 1 year was .22 (95% CI .15-.29). Conclusions The EQ-5D index significantly increased at each time point over 24 months after ≥5 level spinal deformity surgery in elderly patients. The MCID of the EQ-5D-3 L was .22. Patients living at home pre-operatively can expect to be able to live at home 2 years postoperatively.

Funder

AO Spine Knowledge Forum Deformity

AO Spine Research Department

AO Innovation Translation Center, Clinical Evidence

Publisher

SAGE Publications

Subject

Neurology (clinical),Orthopedics and Sports Medicine,Surgery

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3