Correlation between Carotid Artery Mean Intima-Media Thickness and brain Natriuretic Peptide in Patients with Psoriasis-Reference-Cited by-同舟云学术

Correlation between Carotid Artery Mean Intima-Media Thickness and brain Natriuretic Peptide in Patients with Psoriasis

Published:2022-08-08 Issue:4 Volume:7 Page:187-191
ISSN:2475-5303
Container-title:Journal of Psoriasis and Psoriatic Arthritis
language:en
Short-container-title:Journal of Psoriasis and Psoriatic Arthritis

Author:

Niknezhad Nasim¹^ORCID,Shahidi-Dadras Mohammad¹,Rajabi Fateme¹²^ORCID,Khah Hamidreza Haghighat³,Niknejad Nakisa⁴,Younespour Shima⁵

Affiliation:

1. Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

2. Network of Dermatology Research (NDR), Universal Scientific Education and Research Network (USERN), Tehran, Iran

3. Department of Radiology and Medical Imaging Center, Shohada-e Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

4. Department of Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

5. National Institute of Health Research, Tehran University of Medical Sciences, Tehran, Iran

Abstract

Background Numerous studies have documented an association between psoriasis and subclinical atherosclerosis. Objective We aimed to investigate the effects of psoriasis on the levels of N-terminal prohormone B type natriuretic peptide (NT-proBNP) and clarify whether this factor correlates with the evaluations of subclinical atherosclerosis, measured with mean intima-media thickness (MIMT) of the carotid artery. Methods Sixty-one psoriatic patients and sixty-one healthy, age and sex-matched volunteers were enrolled. MIMT was assessed via ultrasonography and serum NT-proBNP level were measured by electrochemiluminescence. Results Both NT-proBNP and MIMT were significantly higher in psoriasis patients. This remained true even after controlling for the effects of age and gender. MIMT was positively correlated with age and serum NT-proBNP level in both groups. Conclusions In conclusion, NT-proBNP levels may be used as a predictor of subclinical atherosclerosis in patients with psoriasis.

Publisher

SAGE Publications

Subject

Dermatology,Rheumatology

Link

http://journals.sagepub.com/doi/pdf/10.1177/24755303221118037

Reference15 articles.

1. Increased risk of arrhythmia in patients with psoriatic disease: A nationwide population-based matched cohort study

2. Can serum level of N‐terminal pro B‐type natriuretic peptide be used in patients with psoriasis as a predictor of cardiovascular disease?

3. Prediction of Clinical Cardiovascular Events With Carotid Intima-Media Thickness

4. Essential biochemistry and physiology of (NT-pro)BNP

5. N-terminal pro-brain natriuretic peptide could be a marker of subclinical atherosclerosis in patients with type 2 diabetes