Insulin Lispro Update

Abstract

PURPOSE This paper provides a review of the literature and clinical studies for insulin lispro and updated information on its advantages over regular insulin for various populations of people with diabetes. METHODS Information was gathered from a search of Medline articles and from review of clinical studies. RESULTS Patients in various special populations using insulin lispro, with proper adjustment of basal insulin, had a greater reduction in hemoglobin Al C and fewer episodes of hypoglycemia than patients on regular insulin. CONCLUSIONS More recently published literature shows that due to its faster onset and shorter duration of action, insulin lispro is useful for not only lowering Al C values, but also for reducing hypoglycemic events in various populations with diabetes, including pediatric and pregnant patients, those with gastroparesis, and insulin pump users.