Should We Preclude Phase 1 Clinical Trials from Enrolling Elderly Individuals?
Author:
Affiliation:
1. Senior Adult Oncology Program, Cancer Control H. Lee Moffitt Cancer Center & Research Institute Tampa, Florida
Publisher
SAGE Publications
Subject
Oncology,Hematology,General Medicine
Link
http://journals.sagepub.com/doi/pdf/10.1177/107327481502200216
Reference20 articles.
1. Enrollment of Elderly Patients in Clinical Trials for Cancer Drug Registration: A 7-Year Experience by the US Food and Drug Administration
2. Adverse events in volunteers participating in phase I clinical trials: a single-center five-year survey in 1,559 subjects
3. Relation between age and clearance rate of nine investigational anticancer drugs from phase I pharmacokinetic data
4. Safety and tolerability of phase I/II clinical trials among older and younger patients with acute myelogenous leukemia
5. Participation and survival of geriatric patients in Phase I clinical trials: The Karmanos Cancer Institute (KCI) experience
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