A Systematic Approach for Post Hoc Subgroup Analyses With Applications in Clinical Case Studies-Reference-Cited by-同舟云学术

A Systematic Approach for Post Hoc Subgroup Analyses With Applications in Clinical Case Studies

Published:2019-06-16 Issue: Volume: Page:216847901985378
ISSN:2168-4790
Container-title:Therapeutic Innovation & Regulatory Science
language:en
Short-container-title:Drug Inf J

Author:

Muysers Christoph¹^ORCID,Dmitrienko Alex²,Kulmann Hermann¹,Kirsch Bodo¹,Lippert Susanne¹,Schmelter Thomas¹,Schulz Anke¹,Mentenich Nicole¹,Schmitz Heinz³,Schaefers Matthias³,Meinhardt Gerold⁴,Keil Thomas⁵,Roll Stephanie⁵

Affiliation:

1. Statistics and Data Insights, Bayer AG, Berlin/Wuppertal, Germany

2. Mediana Inc, Overland Park, KS, USA

3. Clinical Development, Bayer AG, Berlin, Germany

4. Clinical Development Oncology, Bayer AG, Whippany, NJ, USA

5. Institute for Social Medicine, Epidemiology and Health Economics, Charité–Universitätsmedizin, Berlin, Germany

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Public Health, Environmental and Occupational Health,Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Link

http://journals.sagepub.com/doi/pdf/10.1177/2168479019853782

Reference25 articles.

1. Subgroup identification based on differential effect search-A recursive partitioning method for establishing response to treatment in patient subpopulations

2. Treatment effect heterogeneity for univariate subgroups in clinical trials: Shrinkage, standardization, or else

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