Trachyspermum ammi (L.) Sprague-Reference-Cited by-同舟云学术

Trachyspermum ammi (L.) Sprague

Published:2014-10-10 Issue:1 Volume:20 Page:50-56
ISSN:2156-5872
Container-title:Journal of Evidence-Based Complementary & Alternative Medicine
language:en
Short-container-title:J Evid Based Complementary Altern Med

Author:

Moein Mahmoodreza R.¹²,Zomorodian Kamiar³,Pakshir Keyvan³,Yavari Farnoosh¹,Motamedi Marjan¹,Zarshenas Mohammad M.¹⁴

Affiliation:

1. Medicinal Plants Processing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

2. Department of Pharmacognosy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran

3. Department of Medical Mycology and Parasitology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

4. Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy and Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Abstract

Resistance to antibacterial agents has become a serious problem for global health. The current study evaluated the antimicrobial activities of essential oil and respective fractions of Trachyspermum ammi (L.) Sprague. Seeds of the essential oil were extracted and fractionated using column chromatography. All fractions were then analyzed by gas chromatography/mass spectrometry. Antifungal and antibacterial activities of the oil and its fractions were assessed using microdilution method. Compounds γ-terpinene (48.07%), ρ-cymene (33.73%), and thymol (17.41%) were determined as major constituents. The effect of fraction II was better than total essential oil, fraction I, and standard thymol. The greater effect of fraction II compared to standard thymol showed the synergistic effects of the ingredients in this fraction. As this fraction and also total oil were effective on the studied microorganism, the combination of these products with current antimicrobial agents could be considered as new antimicrobial compounds in further investigations.

Publisher

SAGE Publications

Subject

Fluid Flow and Transfer Processes,Building and Construction

Link

http://journals.sagepub.com/doi/pdf/10.1177/2156587214553302

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