A Double-Blind Randomized Placebo-Controlled Feasibility Study Evaluating Individualized Homeopathy in Managing Pain of Knee Osteoarthritis

Author:

Koley Munmun1,Saha Subhranil1,Ghosh Shubhamoy2

Affiliation:

1. Clinical Research Unit (Homeopathy), Siliguri, under Central Council for Research in Homeopathy, Government of India, Gokhel Road, Arabindapally, Siliguri, Darjeeling, West Bengal, India

2. Department of Pathology and Microbiology, Mahesh Bhattacharyya Homeopathic Medical College and Hospital, Government of West Bengal, Howrah, West Bengal, India

Abstract

Few homeopathic complexes seemed to produce significant effects in osteoarthritis; still, individualized homeopathy remained untested. We evaluated the feasibility of conducting an efficacy trial of individualized homeopathy in osteoarthritis. A prospective, parallel-arm, double-blind, randomized, placebo-controlled pilot study was conducted from January to October 2014 involving 60 patients (homeopathy, n = 30; placebo, n = 30) who were suffering from acute painful episodes of knee osteoarthritis and visiting the outpatient clinic of Mahesh Bhattacharyya Homeopathic Medical College and Hospital, West Bengal, India. Statistically significant reduction was achieved in 3 visual analog scales (measuring pain, stiffness, and loss of function) and Osteoarthritis Research Society International scores in both groups over 2 weeks ( P < .05); however, group differences were not significant ( P > .05). Overall, homeopathy did not appear to be superior to placebo; still, further rigorous evaluation in this design involving a larger sample size seems feasible in future. Trial registration: Clinical Trials Registry, India (CTRI/2014/05/004589).

Publisher

SAGE Publications

Subject

Fluid Flow and Transfer Processes,Building and Construction

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