Extended-Release Formulations in Epilepsy-Reference-Cited by-同舟云学术

Extended-Release Formulations in Epilepsy

Published:2007-04 Issue:4 Volume:22 Page:419-426
ISSN:0883-0738
Container-title:Journal of Child Neurology
language:en
Short-container-title:J Child Neurol

Author:

Verrotti Alberto¹,Salladini Carmela²,Di Marco Giovanna²,Pisciella Floriana²,Chiarelli Francesco²

Affiliation:

1. Department of Medicine, Section of Pediatrics, University of Chieti, Italy,

2. Department of Medicine, Section of Pediatrics, University of Chieti, Italy

Abstract

In the past years, the extended-release antiepileptic drug formulations have been developed and then approved for the treatment of many types of epilepsy. Among these extended-release formulations of antiepileptic drugs, the main drugs are valproic acid, carbamazepine, and phenytoin. This review analyzes the chemical and structural characteristics of the extended-release formulations of these 3 antiepileptic drugs, analyzing their bioequivalence and the studies about their clinical use. The results of these studies are encouraging and suggest a good tolerability and efficacy of these extended-release formulations, although larger studies are needed.

Publisher

SAGE Publications

Subject

Neurology (clinical),Pediatrics, Perinatology and Child Health

Link

http://journals.sagepub.com/doi/pdf/10.1177/0883073807302760

Reference69 articles.

1. Annegers JF Epidemiology of epilepsy. In: Wyllie E , ed. The Treatment of Epilepsy: Principles and Practice. 2nd ed. Baltimore: Williams & Wilkins ; 1997:165-172.

2. The relationship between poor medication compliance and seizures

3. Leppik IE Contemporary Diagnosis and Management of the Patient With Epilepsy. 6th ed. Newton, Pa: Handbooks in Healthcare ; 2002:119-127.

4. Standard Approach to Antiepileptic Drug Treatment in the United Kingdom

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