Factor Analysis of the Einstein Neonatal Neurobehavioral Assessment Scale in Infants with Congenital Heart Disease and Healthy Controls-Reference-Cited by-同舟云学术

Factor Analysis of the Einstein Neonatal Neurobehavioral Assessment Scale in Infants with Congenital Heart Disease and Healthy Controls

Published:2022-08-02 Issue:10-11 Volume:37 Page:851-863
ISSN:0883-0738
Container-title:Journal of Child Neurology
language:en
Short-container-title:J Child Neurol

Author:

Tran Nhu N.¹²^ORCID,Desai Jay³,Votava-Smith Jodie K.⁴,Brecht Mary-Lynn⁵,Vanderbilt Douglas L.²,Panigrahy Ashok⁶,Mackintosh Liza⁷,Brady Kenneth M.⁸,Peterson Bradley S.¹⁹

Affiliation:

1. Institute for the Developing Mind, The Saban Research Institute, Children’s Hospital Los Angeles and Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, USA

2. Fetal and Neonatal Institute, Division of Neonatology Children's Hospital Los Angeles, Department of Pediatrics and Keck School of Medicine, University of Southern California, Los Angeles, USA

3. Division of Neurology, Children’s Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, USA

4. Division of Cardiology, Children’s Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, USA

5. School of Nursing, University of California, Los Angeles, Los Angeles, USA

6. University of Pittsburgh Medical Center, Children’s Hospital of Pittsburgh, Pittsburgh, USA and Department of Pediatric Radiology, Children’s Hospital Los Angeles, Los Angeles, USA

7. Division of General Pediatrics, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California, USA

8. Lurie Children's Hospital of Chicago, Anesthesiology and Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, USA

9. Department of Psychiatry, Keck School of Medicine, University of Southern California, Los Angeles, USA

Abstract

Background: Administration of the Einstein Neonatal Neurobehavioral Assessment Scale (ENNAS) can be time-consuming, and items can be highly correlated. We aimed to determine: (1) its factor analytic structure; (2) the validity of the factor structure; and (3) the associations of physiologic measures with factor scores. Methods: A factor analysis reduced 21 ENNAS items into 5 factors in 57 congenital heart disease (CHD) and 35 healthy infants. Multiple linear regressions examined the association of factor scores with group, gestational age, and physiologic variables. Results: 5-factor solution: 1 (Orienting Reflex), 2 (Extensor Axial Tone), 3 (Primitive Reflexes), 4 (Flexor Tone), 5 (Reflexive Tone Around Extremity Joints). Moderate to strong evidence supported: face, discriminant, and construct validity of these factors, with Factor 2 having the strongest. Conclusions: Components of Factor 2 may provide similar information about neonatal development, thus reducing the time for and burden of administration for researchers and clinicians.

Funder

Children's Hospital Los Angeles

Southern California Clinical and Translational Science Institute

National Institute of Nursing Research

Publisher

SAGE Publications

Subject

Neurology (clinical),Pediatrics, Perinatology and Child Health

Link

http://journals.sagepub.com/doi/pdf/10.1177/08830738221115982

Reference62 articles.

1. Neurobehavioral Performance of Lowbirthweight Infants at 40 Weeks Conceptional Age: Comparison with Normal Full term Infants

2. Influence of gestational age, birth weight, and asphyxia on neonatal neurobehavioral performance

3. Neurologic Status of Newborns With Congenital Heart Defects Before Open Heart Surgery

4. Neurodevelopmental status of newborns and infants with congenital heart defects before and after open heart surgery

5. Cerebral Autoregulation in Neonates With and Without Congenital Heart Disease