Valproate-Associated Stomatitis-Reference-Cited by-同舟云学术

Valproate-Associated Stomatitis

Published:2002-03 Issue:3 Volume:17 Page:225-227
ISSN:0883-0738
Container-title:Journal of Child Neurology
language:en
Short-container-title:J Child Neurol

Author:

Ryan Melody¹,Baumann Robert J.²,Miller Craig S.³,Baker Chris⁴

Affiliation:

1. Division of Pharmacy Practice and Science, College of Pharmacy Department of Neurology, College of Medicine University of Kentucky Lexington, Kentucky

2. Department of Neurology and Department of Pediatrics College of Medicine University of Kentucky Lexington, Kentucky

3. Departments of Oral Health Practice and Microbiology and Immunology College of Dentistry and College of Medicine University of Kentucky Lexington, Kentucky

4. Department of Oral Health Science, Pediatric Dentistry Section College of Dentistry University of Kentucky Lexington, Kentucky

Abstract

The purpose of this article is to report a case of severe stomatitis in a patient with pediatric epilepsy taking divalproex sodium. The case was reviewed with detailed oral examinations. This 5-year-old child developed severe stomatitis 18 months after institution of divalproex sodium. Cessation of the medication was associated with resolution of the stomatitis. A review of the pertinent literature is also provided. Stomatitis is a rare but potentially serious adverse effect of divalproex sodium administration. (J Child Neurol 2002;17: 225-227).

Publisher

SAGE Publications

Subject

Neurology (clinical),Pediatrics, Perinatology and Child Health

Link

http://journals.sagepub.com/doi/pdf/10.1177/088307380201700315

Reference14 articles.

1. Valproate-induced stomatitis

2. Erythema multiforme affecting the oral cavity

3. Medication Use and the Risk of Stevens–Johnson Syndrome or Toxic Epidermal Necrolysis

4. Risk of Stevens-Johnson syndrome and toxic epider mal necrolysis during first weeks of antiepileptic therapy: a case-control study

5. Valproic Acid-Induced Stevens-Johnson Syndrome

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