Affiliation:
1. Department of Pediatrics and the Institute for Molecular
Genetics, Baylor College of Medicine, Houston
Abstract
To date over 1,000 cases of Rett syndrome have been described in females exclusively. Some of these cases, less than 2 in 100, are familial. The inheritance through maternal lines in the familial cases suggests that Rett syndrome is an X-linked disorder lethal in males. Hypotheses about the genetic mechanisms involved in this syndrome along with suggestions to approach the molecular basis of this disorder are presented. (J Child Neurol 1988;3(Suppl):S76-S78).
Subject
Clinical Neurology,Pediatrics, Perinatology, and Child Health
Cited by
45 articles.
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