Norepinephrine and Dopamine Metabolites and Educational Variables in Boys With Attention Deficit Disorder and Hyperactivity

Author:

Shekim Walid O.1,Sinclair Esther1,Glaser Robert2,Horwitz Ellen2,Javaid Javaid3,Bylund David B.4

Affiliation:

1. UCLA Child Psychiatry and Mental Retardation program, Los Angeles

2. MidMissouri Mental Health Center and Department of Psychiatry

3. the Illinois State Psychiatry Institute, Chicago

4. Department of Pharmacology University of Missouri-Columbia School of Medicine, Columbia, MO

Abstract

The present study evaluated the biochemical measures of urinary homovanillic acid (HVA) and 3-methoxy-4-hydroxyphenylglycol (MHPG) in relation to functioning on selected psychoeducational tests in a group of boys with attention deficit disorder and hyperactivity. The Wechsler Intelligence Scale for Children-Revised (WISC-R), the Wide Range Achievement Test (WRAT), and the Peabody Picture Vocabulary Test were administered to 28 hyperactive and 23 control subjects. The findings suggest subtle differences in psychoeducational test performance in relation to specific levels of homovanillic acid and MHPG. ( J Child Neurol 1987;2:50-56).

Publisher

SAGE Publications

Subject

Clinical Neurology,Pediatrics, Perinatology, and Child Health

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