Frontal Lobe Cavernous Malformations in Pediatric Patients: Clinical Features and Surgical Outcomes

Author:

Wang Chengjun1234ORCID,Zhao Meng1234,Wang Jia1234,Wang Shuo1234,Jiang Zhongli1234,Zhao Jizong1234ORCID

Affiliation:

1. Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

2. China National Clinical Research Center for Neurological Diseases, Beijing, China

3. Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China

4. Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China

Abstract

The purpose of this study is to investigate the clinical manifestations, surgical treatment, and neurologic outcomes of frontal lobe cavernous malformations in children. A retrospective analysis of 23 pediatric frontal lobe cavernous malformation patients who underwent surgical treatment in Beijing Tiantan Hospital was performed. The case series included 16 boys and 7 girls. Gross total removal without surgical mortality was achieved in all patients. The mean follow-up period after surgery was 33.1 months. Two patients who left hospital with motor deficits gradually recovered after rehabilitative treatment, and other patients were considered to be in excellent clinical condition. For symptomatic frontal lobe cavernous malformations, neurosurgical management should be the treatment of choice. Conservative treatment may be warranted in asymptomatic frontal lobe cavernous malformations, especially the deep-seated or eloquently located cases.

Funder

National Natural Science Foundation of China

Publisher

SAGE Publications

Subject

Neurology (clinical),Pediatrics, Perinatology and Child Health

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