Neuromuscular Blockade in the Management of Cerebral Palsy

Author:

Koman L. Andrew1,Mooney James F.1,Smith Beth Paterson1

Affiliation:

1. Department of Orthopaedic Surgery, Division of Surgical Sciences, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC

Abstract

Neuromuscular blocking agents-45% alcohol, 4% to 6% aqueous phenol, local anesthetics, and botulinum A toxin—have been used for many years in the evaluation and management of spasticity and movement disorders in children with cerebral palsy. Recent reports suggest that longer-acting neuromuscular blocking agents may impact positively on the natural history of dynamic deformity and improve health-related quality of life. This review includes the mechanism of action, techniques, indications, complications, and clinical outcomes associated with these agents. (J Child Neurol 1996;11(Suppl 1):S23-S28).

Publisher

SAGE Publications

Subject

Neurology (clinical),Pediatrics, Perinatology and Child Health

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1. Spasticity evaluation and management tools;Muscle & Nerve;2023-02-19

2. Cerebral Palsy;Movement Disorders in Childhood;2022

3. A consensus statement on the use of botulinum toxin in pediatric patients;PM&R;2021-11-26

4. Botulinum Toxin in the Management of Children with Cerebral Palsy;Pediatric Drugs;2019-07-01

5. Cerebral Palsy;Movement Disorders in Childhood;2016

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