“How Much Brain Is Really Necessary?” A Case of Complex Cerebral Malformation and Its Clinical Course

Author:

Distelmaier Felix1,Richter-Werkle Renate2,Schaper Jörg3,Messing-Juenger Martina4,Mayatepek Ertan2,Rosenbaum Thorsten2

Affiliation:

1. Department of General Pediatrics, Heinrich-Heine-University, Dusseldorf, Germany, -duesseldorf.de

2. Department of General Pediatrics, Heinrich-Heine-University, Dusseldorf, Germany

3. Department of Diagnostic Radiology, Heinrich-Heine-University, Dusseldorf, Germany

4. Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

Abstract

The clinical manifestations of cerebral malformations are complex and vary from mild retardation to massive disabilities. A review of the literature suggests that the developmental outcome in these patients depends on the extension, location, and combination of such anomalies. However, the authors present the encouraging clinical course of a girl with a complex cerebral malformation. Despite the severe imaging findings, at the present age of 34 months, the patient developed only a mild psychomotor retardation. This case illustrates that the morphological classification of cerebral malformations does not allow one to predict with certainty whether a child will develop impaired motor and/or higher cognitive functions.

Publisher

SAGE Publications

Subject

Neurology (clinical),Pediatrics, Perinatology and Child Health

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1. Archetypes and the ‘Impoverished Genome’ argument: updates from evolutionary genetics;Journal of Analytical Psychology;2020-11

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4. Programmation du Suivi Pédiatrique du Développement du Jeune Enfant;Démarche clinique en neurologie du développement;2009

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