Cortical Dysplasias, and Corpus Callosum and Posterior Fossa Abnormalities

Abstract

This study examined clinical findings and magnetic resonance imaging (MRI) characteristics in 114 patients with cortical dysplasia and corpus callosum and posterior fossa abnormalities to determine the clinical findings with the extent of the lesions on MRI. The age of patients was between 1 day and 15 years. Group 1 included 74 patients with corpus callosum abnormalities and/or cortical dysplasias and group 2 included 40 patients with posterior fossa abnormalities, which were isolated and/or associated with cortical dysplasia and/or corpus callosum abnormalities. Although associated congenital abnormality apart from central nervous system abnormalities, syndrome, or systemic disorder were more common in group 2 than group 1 patients ( P < .05), we did not find a difference between the groups for psychomotor retardation and epilepsy ( P > .05).