Treatment of Sydenham Chorea With Intravenous Immunoglobulin-Reference-Cited by-同舟云学术

Treatment of Sydenham Chorea With Intravenous Immunoglobulin

Published:2011-08-24 Issue:2 Volume:27 Page:147-155
ISSN:0883-0738
Container-title:Journal of Child Neurology
language:en
Short-container-title:J Child Neurol

Author:

Walker Kathleen¹²,Brink Anita³,Lawrenson John⁴,Mathiassen Wendy¹²,Wilmshurst Jo M.²

Affiliation:

1. Rheumatic Fever Clinic, Department of Cardiology, Red Cross Children’s Hospital, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa

2. Department of Neurology, Red Cross Children’s Hospital, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa

3. Department of Nuclear Medicine, Red Cross Children’s Hospital, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa

4. Department of Paediatrics and Child Health, Stellenbosch University, Paediatric Cardiology Service of the Western Cape, South Africa

Abstract

Sydenham chorea is a post-streptococcal, autoimmune, neuropsychiatric, movement disorder. There is no effective treatment. In a randomized study, comparison was made of the outcomes of 10 children treated with standard management alone compared to 10 who received additional intravenous immunoglobulin. The outcomes were assessed using a clinical rating scale, brain single-photon emission computed tomography, and the duration of symptomatic treatment. All three outcome measurement tools found improved outcomes in the group that received intravenous immunoglobulin.

Publisher

SAGE Publications

Subject

Neurology (clinical),Pediatrics, Perinatology and Child Health

Link

http://journals.sagepub.com/doi/pdf/10.1177/0883073811414058

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4. The natural history of Sydenham's chorea

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