Upper Extremity Multifocal Neuropathy in a 10-Year-Old Boy Associated With NS6S Disaccharide Antibodies-Reference-Cited by-同舟云学术

Upper Extremity Multifocal Neuropathy in a 10-Year-Old Boy Associated With NS6S Disaccharide Antibodies

Published:2014-07-17 Issue:7 Volume:30 Page:945-948
ISSN:0883-0738
Container-title:Journal of Child Neurology
language:en
Short-container-title:J Child Neurol

Author:

Edelman Frederick¹,Naddaf Elie²,Waclawik Andrew J.³

Affiliation:

1. Child Neurology Division, Department of Neurology, University of Wisconsin Hospital and Clinics, Madison, WI, USA

2. Neurology Resident, Department of Neurology, University of Wisconsin Hospital and Clinics, Madison, WI, USA

3. Neuromuscular Division, Department of Neurology, University of Wisconsin Hospital and Clinics, Madison, WI, USA

Abstract

We present a 10-year-old boy with a predominantly motor multifocal neuropathy with demyelinating and axonal changes with sensory involvement, affecting only one upper extremity. Laboratory studies revealed an elevated titer of immunoglobulin M (IgM) antibodies against the NS6S antigen. He responded to treatment with high dose intravenous immunoglobulins. Focal or multifocal immune-mediated neuropathies are not common in children and may be underdiagnosed.

Publisher

SAGE Publications

Subject

Neurology (clinical),Pediatrics, Perinatology and Child Health

Link

http://journals.sagepub.com/doi/pdf/10.1177/0883073814541472

Reference10 articles.

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3. Focal upper limb neuropathy in a child

4. Idiopathic Neuralgic Amyotrophy in Children. A Distinct Phenotype Compared to the Adult Form

5. Multifocal motor neuropathy

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