Dermatomyositis in Two Siblings and a Brief Review of Familial Dermatomyositis

Author:

Tsao Chang-Yong1,Mendell Jerry R.2,Kissel John T.3

Affiliation:

1. Departments of Pediatrics and Neurology The Ohio State University

2. Department of Neurology The Ohio State University

3. Department of Neurology The Ohio State University Columbus, Ohio

Abstract

Juvenile dermatomyositis is an uncommon autoimmune disease with classic heliotrope discoloration of the eyelids, erythematous skin rash of joints, and proximal muscle weakness. It is most frequently sporadic and only rarely familial. We present juvenile dermatomyositis in a 5-year-old brother and a 3½-year-old sister; both are very responsive to corticosteroids. Familial dermatomyositis can occur in different family members, and even dermatomyositis and polymyositis can coexist in the same family. (J Child Neurol 2002;17:540-542).

Publisher

SAGE Publications

Subject

Clinical Neurology,Pediatrics, Perinatology, and Child Health

Reference29 articles.

1. Engel AG, Hohlfeld R., Banker BQ: The polymyositis and dermatomyositis syndrome, in Engel AG, Franzini-Armstrong C (eds): Myology. New York, McGraw-Hill, 1994, 1335-1383.

2. Cassidy JT: Juvenile dermatomyositis, in Cassidy JT, Petty R (eds): Textbook of Pediatric Rheumatology . Edinburgh, Churchill Livingstone , 1990,331-375.

3. Dalakas MC: Clinical features, pathogenesis, diagnosis, and treatment of the inflammatory myopathies, in Younger DS (ed): Motor Disorders. Philadelphia, Lippincott Williams & Wilkins, 1999, 113-122.

4. Amyopathic Dermatomyositis: A Review

5. Dermatomyositis of Childhood

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