Coma Blisters in 2 Children on Anticonvulsant Medication

Author:

Basu Anna1,Brown Sara2,Kirkham Nigel3,Ramesh Venkateswaran4,Leech Suzy2,Devlin Anita4

Affiliation:

1. School of Clinical Medical Sciences (Child Health), Newcastle University, United Kingdom, , Department of Paediatric Neurology, Newcastle General Hospital, Newcastle Upon Tyne, United Kingdom

2. Department of Dermatology, Royal Victoria Infirmary, Newcastle Upon Tyne, United Kingdom

3. Department of Cellular Pathology, Royal Victoria Infirmary, Newcastle Upon Tyne, United Kingdom

4. Department of Paediatric Neurology, Newcastle General Hospital, Newcastle Upon Tyne, United Kingdom

Abstract

Blister formation and eccrine sweat gland necrosis have been recognized to occur in states of impaired consciousness and were first reported following barbiturate intoxication. Their etiology is complex and cannot simply be explained by pressure effects. Now that barbiturates are less frequently used, clinicians are likely to be less aware of the phenomenon of coma blister formation; however, newer drugs have also been associated with the occurrence of coma blisters. We describe 2 new associations of coma blisters and anticonvulsants in children. In the first child, blisters recurred on multiple occasions along with obtundation and edema. Our aims are to alert clinicians to the occurrence of coma blisters in children sedated on anticonvulsant medications and to report the new finding of recurrent coma blisters.

Publisher

SAGE Publications

Subject

Clinical Neurology,Pediatrics, Perinatology, and Child Health

Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Toxicology of Specific Substances;Handbook of Forensic Medicine;2022-06-27

2. Drug Repurposing by Simulating Flow Through Protein-Protein Interaction Networks;Clinical Pharmacology & Therapeutics;2017-07-29

3. An update on pediatric cutaneous drug eruptions;Clinics in Dermatology;2014-07

4. Toxicology of Specific Substances;Handbook of Forensic Medicine;2014-03-14

5. Bullous lesions, sweat gland necrosis and rhabdomyolysis in alcoholic coma;Indian Journal of Dermatology;2014

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3