Phenytoin-Associated Thrombocytopenia in a Toddler-Reference-Cited by-同舟云学术

Phenytoin-Associated Thrombocytopenia in a Toddler

Published:1999-02 Issue:2 Volume:14 Page:130-131
ISSN:0883-0738
Container-title:Journal of Child Neurology
language:en
Short-container-title:J Child Neurol

Author:

Alehan Füsun K.¹,Russell Edward C.²,Pellock John M.³

Affiliation:

1. Division of Child Neurology

2. Division of Pediatric Hematology- Oncology

3. Division of Child Neurology Medical College of Virginia of Virginia Commonwealth University Richmond, VA,

Abstract

Hematologic side effects are rare side effects of treatment with phenytoin. We report a 2-year-old girl who developed reversible thrombocytopenia following treatment with phenytoin. Thrombocytopenia as a side effect of phenytoin treatment has usually been reported in adults and generally occurs 2 to 4 weeks after initiation of therapy. In our case, the thrombocytopenia developed on the 11th day of therapy and resolved 5 days after discontinuation of the phenytoin. (J Child Neurol 1999;14:130-131).

Publisher

SAGE Publications

Subject

Neurology (clinical),Pediatrics, Perinatology and Child Health

Link

http://journals.sagepub.com/doi/pdf/10.1177/088307389901400212

Reference9 articles.

1. Pisciotta AV: Phenytoin: Hematological toxicity, in Woodbury DM, Penry JK, Pippinger CE (eds.): Antiepileptic Drugs. New York, Raven Press, 1982, pp 257-268.

2. Drug-induced Thrombocytopenia

3. Drug-induced thrombocytopenia is associated with increased binding of IgG to platelets both in vivo and in vitro

4. Severe Thrombocytopenia Due to Combined Cimetidine and Phenytoin Therapy

5. Thrombocytopenia following administration of phenytoin, dexamethasone and cimetidine: a case report and a potential mechanism

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Anticonvulsant drugs and hematological disease;Neurological Sciences;2014-03-12

2. Simultaneous Toxicities in a Child on Multiple Anticonvulsants;Journal of Child Neurology;2008-02-20

3. Fatal phenytoin-induced thrombocytopaenia in a neurosurgical patient;European Journal of Anaesthesiology;2007-10

4. Myokymia and neuromyotonia in a cat;Journal of the American Veterinary Medical Association;2005-11

5. Enterocolitis: an adverse event in refractory epilepsy patients treated with levetiracetam?;Seizure;2004-03