The New Bilayer Lipid Membrane System: Self-Assembling Bilayer Lipid Membranes

Author:

Ti Tien H.1,Salamon Z.1,Guo D.-L.1,Ottova-Leitmannova A.1

Affiliation:

1. Membrane Biophysics Lab. , Giltner Hall Department of Physiology Michigan State University East Lansing, MI 48824

Abstract

Supported bilayer lipid membranes (s-BLMs) were formed by the self- assembly method on freshly fractured metallic wires. The influence of a host of com pounds in membrane forming solutions on s-BLMs and the effect of pH on the function of the s-BLM were studied. Additionally, the redox reactions of a s-BLM containing vinyl- ferrocene as an electron mediator have been investigated by cyclic voltammetry. The results have shown that ferrocene can be very easily immobilized in s-BLMs. This sug gests that s-BLM systems offer a novel approach to the electrode modification by simple way of immobilization of compounds within BLM.

Publisher

SAGE Publications

Subject

Mechanical Engineering,General Materials Science

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