Neurological Complications of Aortic Surgery

Abstract

Surgery of the aortic arch involves an inherently high risk of neurological complications. A number of factors have been identified which may predispose the patient to brain injury, and various techniques employed in an attempt to counteract these are outlined. In particular the vulnerability of the brain to ischemia has led to the development of three adjunctive cerebral protective techniques, hypothermic circulatory arrest, retrograde cerebral perfusion and selective antegrade cerebral perfusion, all based upon brain cooling and metabolic inhibition. The relative merits and disadvantages of these techniques are therefore discussed. Finally, pharmacologic adjuncts and potential future developments in aortic arch surgery are discussed.